Rebus Group is in discussions to make more than 50 staff redundant in its UK offices.
The job cull will be the second in three months and follows insurers' decisions not to invest in new technology.
In September, the global software and services supplier made between ten and 20 people redundant. They worked primarily on e-business related activities.
Now a further 60 staff worldwide face risk of redundancy, with 95% of the casualties from the UK arm.
Rebus business development director Richard Clark said: "There has been a slowdown in technology that has resulted from the dotcom world collapsing and insurers deferring new business decisions. We believe the actions we are currently taking are sufficient."
He said staff had been notified job cuts would be made, particularly relating to programmers, account managers and business analysts. Attempts would be made to re-employ them elsewhere in the company.
Clark added redundancies would be "at all levels, including senior". The consultation process should be completed by early January.
Rebus trades in more than 40 countries and employs 1,800 people. It has a combined turnover of more than £115m.
Room currently employs about 100 people. Last year it had a £9m turnover.